A study in mice has found that high doses of the sweetener sucralose can reduce the immune response and, under certain laboratory conditions, alter its action against infections or tumours. The results are published in the journal Nature.
Splenda: Common sweetener may suppress immune system in rodent study
Artificial sweeteners may tip scales toward metabolic problems
High sucralose intake suppresses autoimmunity and promotes tumor growth by limiting T cell‐mediated immune responses - Lin - 2023 - MedComm – Future Medicine - Wiley Online Library
Splenda: Common sweetener may suppress immune system in rodent study
Daily briefing: Common sweetener reduces immune response in mice
Nutrients, Free Full-Text
High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice, Microbiome
High sucralose intake suppresses autoimmunity and promotes tumor growth by limiting T cell‐mediated immune responses - Lin - 2023 - MedComm – Future Medicine - Wiley Online Library
Common Artificial Sweetener Sucralose Found to Impact T Cell Immune Response In Mice. Potential Therapeutic For Autoimmune Diseases? - Thailand Medical News
High consumption of common artificial sweetener lowers activation of T-cells in mice
Sucralose treatment limits T cell-specific responses in vivo a–c, CD8
Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice
Commonly used sweetener has 'unexpected effect on immune system', say scientists
Frontiers Low Dose of Sucralose Alter Gut Microbiome in Mice
Researchers discover the immunity-boosting benefits of Sucralose