Targeting by PG545 enhances PARP inhibitor response in ovarian cancer

HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer

PG545 sensitizes ovarian cancer cells to PARP inhibitors through modulation of RAD51-DEK interaction

Cancers, Free Full-Text

Sulfated glycolipid PG545 induces endoplasmic reticulum stress and augments autophagic flux by enhancing anticancer chemotherapy efficacy in endometrial cancer - ScienceDirect

PARP inhibitors: enhancing efficacy through rational combinations

HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer

Fighting resistance: post-PARP inhibitor treatment strategies in ovarian cancer - Ana C. Veneziani, Clare Scott, Matthew J. Wakefield, Anna V. Tinker, Stephanie Lheureux, 2023

Full article: Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer stem cells

Cancers, Free Full-Text