The Role of the Prefrontal Cortex in Chronic Pain - The Pain PT

When looking at the brain’s impact on chronic pain, we have to look to the prefrontal cortex. 2020 review of the research says: ‘Its predominant role in aversive learning and memory puts the medial prefrontal cortex (mPFC) in a pole position as a hub for the development of mental comorbidities associated with chronic pain.’  The […]

The Role of the Prefrontal Cortex in Chronic Pain - The Pain PT

Fearful memories of pain stored in the prefrontal cortex could

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Microcircuit Mechanisms through which Mediodorsal Thalamic Input

Multiple brain regions moderate and link depressive mood and pain

The pain matrix (modified from Melzack 2005) and the highlighted

IJMS, Free Full-Text

Cannabidiol in the prelimbic cortex modulates the comorbid

Frontiers Sex differences in chronic pain-induced mental

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How Chronic Pain Rewires the Brain and 5 Proven Ways to Reverse It

Examining resting-state functional connectivity in key hubs of the

Trauma & Chronic Pain, WakeMed Health & Hospitals, Raleigh & Wake